Pregnenolone

Pregnenolone 145-13-1

Pregnenolone
CAS: 145-13-1
MF: C21H32O2
MW: 316.48
EINECS: 205-647-4
MP: 188-190 ° C
Alpha: 28.5 º (c=1, EtOH)
Storage temp.: Refrigerator
Merck: 7733
Chemical Properties: White to off-white powder

Pregnenolone.jpg
Pregnenolone is a steroid hormone involved in the steroidogenesis of progesterone, mineralocorticoids, glucocorticoids, androgens, and estrogens. As such it is a prohormone. Pregnenolone is a GABAA antagonist and increases neurogenesis in the hippocampus.

Like other steroids, pregnenolone consists of four interconnected cyclic hydrocarbons. It contains ketone and hydroxyl functional groups, two methylbranches, and a double bond at C5, in the B cyclic hydrocarbon ring. Like all steroid hormones, it is hydrophobic. Its esterified version, pregnenolone sulfate, is water-soluble.

 

 

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